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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '053c271b897454b6d7d5283fc76c6172f9d6d02c343ac2aa94ed3beb2c959949' 
  AND token = 'tBFzIC71pMcq9yxoJDWVn2DxCXpaldLmaN8q4q7gfM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}