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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '56f65d89ac4e6d58c53ee8babf287b11cedcbb29a1ceb5ce56018687d7ed5def' 
  AND token = '3eZO1+ISULIQsydSyb9LPkD1di++cqRop/7JK6UKRiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}