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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe63226b7a74477b2ef9bf7b0c809f134f9c659ac67e4fa45102615514be0116' 
  AND token = 'BNxpzkWPgjqzHKppX4FeID4uioUbS9N4cNgNDmyK2Bs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}