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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab10e3c1135c5b9d15b45cd67f860dc447ec282e23e1d8b83021cc2226d9dea9' 
  AND token = 'vaXswTPfrmdjL5tmBRMAA0GpB1AEJAE66q/ZPkLjDcg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}