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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51b604bb15ef31b9a83eec65f91fde36e5b603015efdf0744fd7c7dda45af8b7' 
  AND token = 'toAvbVTOSPL4VHh9QW1tO1TyfDoBkoKiL7XW8/7KpgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}