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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '122aed7f3ffaf0d0bb087e2de7d967ba02c215acf21e2b0d16fda0d0cef969f7' 
  AND token = 'NS4WFqvk+5cQNvz1qoQMDgK1SkPTZs4qauysv+O9sgA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}