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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1de0afe1e0b39c0c47cedf00212ad464fb7e1bc30439ee34e16f6daa205f2367' 
  AND token = 'OXBzyLi1WMZV6U9CnyBzdB3PhtINneMfmx8VWpn1jbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}