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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '653349382672b3ba3b53f7ec6df5eba9d44d4e8b0b04837fa47cbf6a1c7933a1' 
  AND token = 'CsUf49EyFpnjh8j/5lEknhygTBAOCQAugnfNlShiixA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}