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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a2821c4f88c321d2f67598c07b497fda57595929f2573b790062fde73e5d2b1' 
  AND token = 'GRWhj6Vb368O2WdfEJ7w4oH00ot3QpUIyIUp01FxfCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}