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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39837943e6d19fc6e6cfb4b6b46a8b9917ec3ec082648689824d21a8f72dd337' 
  AND token = 'VJHiX5Znv2Qhx13po2EhnbVNjl+n1hz564IimrdlCR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}