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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3509b60aefe929ef70593388cc887ac1e5a36dba2b0a3ca5dbe524de3e714d3d' 
  AND token = 'l1yxVUx545AqOpHy3EB5M/xC+u+Rm/OStpt3nmpAASg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}