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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eeed4d4f1c1181514ba7ce377fad55e24f878f783baa2b3df197e3330147563f' 
  AND token = 'cfbP8O6bvxMpOEQi0v9pxu4uX3f82aOMiCaz3D6Bwps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}