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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21c0a7bc281d7880334def6b507058c911b01b32512a9c2492d2e3dd98617b3b' 
  AND token = 'e8CLED9lPuLhGBkkgdlFs4dC1lxEb/wo/cQIx5wzn0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}