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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '608218d1ba887d231f27b3185b60b870f815f143d7593d8d1bfbd640a1c02d2b' 
  AND token = 'Rl2pRBmCfyv6osVmN2nb8jZOwjyRW51fno0Yvcw69D8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}