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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18d7f57975d5a88c11b21e7bd41daad11b27ab8d3b684b9791b60f77ef9b5394' 
  AND token = '3Ys5IDMwm0D3TpcZ1E46VGuwR8v2qd+LsHOmrc6utk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}