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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f4ed74d213a4f75b2d7911049e074562eebb1a62f019f76f6e48fce903901e5' 
  AND token = 'y6zYnjwlFzEQ/eE3iHPOjuypPDFpARo7U/BnUp9OKu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}