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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c1a90722f30d53be1549e85e67cd3ec57fcb9d6c3515b045fa9dbdf1b41b5c8' 
  AND token = '1Ze/lAWN0l9BsWHYblsR3HWfwb9kdDgOrm+O2m9w4lU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}