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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdfd0c1764646f4f9f3b213910de00546928b84ed04b238a6fe2ed9538735181' 
  AND token = 'YylZL90xpOvdp40WK55y6kWN5QH0eBL3+jfVHZzzNR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}