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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d676a4096787776b96d20c28ab262e5b09736f0389f168f8852862cdfae78ed' 
  AND token = 'MiZfHMZX0IOqQmnuLs10Xu+3fDPiC9h99MTc9KHVry0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}