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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b9a75e68fe5ee1f8bbcd3fcda89569d7e48dfd338a383cff5cc7a12a86f9249' 
  AND token = 'Hpqt+HVk5BZ3MFNDDOSeze4fSVng5p8kxZ3vBdll/+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}