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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '168c25173de273b496c0bb98249db08af13fca41109b38f258aecad591960e1a' 
  AND token = 'q+CnBqHzEIsicQfPQ0/0tT9A3Pa/XFSzRk9+0+PozMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}