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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e360d738066c00ceea1859f271b9d0da5ea6b823fea819c9b8a16152e26225a2' 
  AND token = 'y25Z1t8iYTvlzbQDnRJh+NYYWqas2IjZbc/5ZyhEoIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}