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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '348abe295bad42795d82302bf5fef984f9f242d2c9c0a7bf6644fc8ce8dc5c14' 
  AND token = 'ktmqBis2tkycg4xLg1zyXkmfeOeNtB/vmWKVSPYdAiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}