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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bee043dfce57ee447547f4e16a5f255a3984bc909f25bae0eed2c29582a98e22' 
  AND token = 'IlFqsdNCxNkhCdyGDr8ldKMPfh7haix0RXhH5u2ZsoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}