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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a49d69cd507d98a6abd86672159fcca8055cd4a16dfa211f48b8eb674b69a15' 
  AND token = 'bL0tXqzPVa8FZJXms/OWS+PZo+Vk1Og6E2hw2zbTPwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}