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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afd32f4280cdee0c71ea59227eaefaaf5e230f32ebe88f3ddc61adedca8850bd' 
  AND token = 'ns4mRIFhOQKIP4GxKLGrx9jY47qVBsiCXbZ/h5jcPQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}