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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '782b29a074f2bd7eed7fe779e7ff2353e9310c1bcc43cb8114c218c647ee7446' 
  AND token = '+YkUbHAW84yp4oBBAUNS3NTu2pB4Ch5hsG1SaEJ5aX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}