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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3943ed54a5eb8b97fb9e05117a7f974b18325d7d21f85e70b0f0abfbfff475ec' 
  AND token = 'zNbgtz8yeugkS/NIMBpBwdIhQsrHR9g3wGFj00BrPpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}