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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd099d4bcf35a94849345d16c5ccc8b36f3c352bf3fd65c784c72ec000cf2de88' 
  AND token = 'y57TZBQ5zKvNjhXEe9d3fC+8XX1hRq+ubWN7Xk2ye8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}