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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3ca2c9ff9fc340374f6a2e6971f493f57123a2c8c8c1fd3dad7963759bc8def' 
  AND token = 's+IucyQMOm6uKbUn8RTXyZgmOgGZNwiBLHSTbn8jnDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}