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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d6bdfe3e52262fef922b91bb639ba9abda7c726a9a8ac24abf0d954b5d39740' 
  AND token = 'VtpCCl8+F59eqI6EqYC1TWOqSBY0OYXDBPAJseRZfaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}