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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63e7d831be10d349e56da2ef8fcbfb3c0b21d430175d29959e6be9ab1613efa5' 
  AND token = 'V0q8DjeOksDwWhTdlCP/klWoT7z2jMNVYNVf0pyz99Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}