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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6600e4d9f103c88519a371fcf352bc96ac2677d94787a1684096cd20b0ec8d5c' 
  AND token = 'NTEweA9PDpUID1I5/2PNbsHIdM54KT9yva+nmvj+DSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}