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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73a099588b09e4b4b1606052d8bb420ea7fac515d0acb90a0ee2c73100ea9285' 
  AND token = 'coCSvXbJdMVtKTkwrS85a9Qg5r9oH4Izq3sW8+3Aq5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}