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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5ac80c045797d12374b85a3006a8fd2e2b234f20cf9b94ea124f193b0ea6804' 
  AND token = 'ocXWKSl/PMeEUttHvAUnsfYA7zBqC7RVk+Mr4D4NyNc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}