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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd16e1a798f7fa228d410f4d0ba02882fbed3f12f425473f44e1af01cb7113563' 
  AND token = 'gqFp7Ig9Oke8a33WY4RZjNqeh1HoVnrcQ0lpB1wQDKk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}