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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00c23cb6146003403bf1da72060f50f04cb60f4d15ef97a8df3a492c84c3b094' 
  AND token = 'XxAV7AqhhoyLVwhROrmpN8S8uI6j0TaVj0LESSY9uZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}