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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d3d0f66a681cdfcd183c6bdc181bac53ae5eb1c1698eeabbac97e426ce5a218' 
  AND token = 'Mk3tyIt0ua9T8/Wn0AC6+gy5+RRNvwK/qFAzl6HNUEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}