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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fcbb9c7468f3f6d034597be3a03c0368d398fcd5454e6749eb82553e8856f250' 
  AND token = '2iYB2WYmmB78xGUCKrRnyXJmfXtSVkWuMp3q9Pa5mBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}