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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4547343c94958771950391474d9b839a5b5f57c9dab6a2f78974acd526a98af0' 
  AND token = 'PvSYyXyi5TKHCV1a6RJNTpQ+BsE0HvOdGdEZ47+vjlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}