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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e2730e5d192e3518b5fa848e1082aff39de079b5e8f6bafa402151e6b2ddc36' 
  AND token = '/kaz0MHD1khUuZEFcEBHbQ+bS4uURNVZ0xvsHtkH0MM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}