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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64c8f39352f74fe1823f7f68bd8f7787d3c621cbc16f5a0e30093317febbd5e9' 
  AND token = 'GfOERVcrWkCW4eHOXzMdkVxGL61FADXS6WNPbsCSU5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}