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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e42a649d842b7f9d61c5dde92a37d7e447e672305809144b6f9e25be569631ea' 
  AND token = 'ztBGgCOA4UpkrbH43svjSro3wLfTaHMAAmA242KwFVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}