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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aca8097cfa4628ea8902b9a489e345839a543b0aaac2430b04395009ace5855a' 
  AND token = '7k6yFrRlqVCQkojz7nnelMYIvFnHKHEMzzWM3vbmzss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}