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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8236c2ba47e21bb39e2531da09bfd28a11ff5a49004b454df76f793fe66c159c' 
  AND token = '/c/ZM9+cGF8cFPWJcZ+cOp3U+ORZJ//puPOLADFXYfA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}