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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad1759e32258838c2713641c15621f8d3527bcdc2f58f5d2cc9be3bf09653b0d' 
  AND token = 'JoYqz4/wcg3rCX0dDFmHxplmtUhxZO4dpfX1zCxF1yc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}