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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b080a5e6b616e872abcaf83d3630ac1967747f74000559d978ad4ded126900a5' 
  AND token = '20HZJYeAhk0HooSGnUvmHC2lFKiO+yCgBrM7LqNg1FE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}