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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fda9ae35a075744eb9922056a1050cdecdd3ba86406341d43bfb9c50417a4ce5' 
  AND token = 'Ii84XGiaESqH9m/Vd0qrdUH/S0oiYlQ+FoteNKU28Vw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}