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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd626543ebd359f0f7126ee6350f2c8aefa1288dceed541267fb3b01c9e2f730' 
  AND token = '+MDjdzX4ABMLCfFejDRnVhwz7rQCtU295LOToPGoQyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}