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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a72e07d56cc794dbc2ac5a215307e38279124d53177a30c524837f1e93c895f' 
  AND token = 'wKsVRI9G6m2+vAuZTCDoi9CTtNS4M00xP7Gy1ZZ6J4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}